Wes Streeting has called for the UK to rejoin the EU as he laid out his bid to No 10 in a much anticipated speech this weekend.
The former health secretary said he will be running for Labour leader after dramatically quitting his role as a Cabinet minister earlier this week.
He said leaving the EU was a “catastrophic mistake” as he stressed it was time for the UK to build a new “special relationship” with the Union, adding that Labour risks risks becoming “handmaidens” to Nigel Farage in the next general election.
It comes as Andy Burnham said he is standing in the Makerfield by-election to "save" Labour, warning that the party has "not been good enough".
The move will take the Greater Manchester mayor one step closer to taking on Mr Streeting as they both challenge Sir Keir Starmer for the leadership of the party.
Mr Burnham is expected to drop his call to reverse Brexit, as allies of the mayor are reported to have been told he is not going to be “going big on Europe” in his pitch to voters and the country.
